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The 200 to 500mcg figures widely used across clinic and community contexts are derived from animal extrapolation and accumulated self-experimentation, not controlled human trials
Because they come from food, supports like Berberine, Flavonoids, and special probiotics are remarkably safe and have a very low incidence of side effects
doi: 10.1038/s41421-022-00495-y 457 WuS.SongR.LiuT.LiC
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