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Statements Data availability statement Publicly available datasets were analyzed in this study

Weight regain varies by individual, but many people begin regaining weight within the first few months after stopping semaglutide, with the early months representing the highest-risk period

Subsequently, a natural active peptide, glycyl-l-histidyl-l-lysine-Cu (GHK-Cu), was loaded, and an all-natural composite hydrogel dressing, EW/OKGM@GHK-Cu (GEK), was developed