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The effect of acylcarnitine on insulin sensitivity is also related to the saturation of acylcarnitine, with myotubes incubated with C16-carnitine exhibiting reduced insulin sensitization, whereas the accumulation of oleoylcarnitine (C18:1-carnitine) and linoleoylcarnitine (C18:2-carnitine) increases insulin sensitization [77]

1 The largest populations of permanent residents at high altitudes are found in the Andes of South America, the Qinghai-Tibet Plateau, the Caucasus of Eastern Europe, Ethiopia, and the Himalayas

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