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However, he eventually stopped taking retatrutide after a negative experience that he attributes to the drugs interaction with a proton pump inhibitor he was taking to manage acid refluxitself the result of some anabolic steroids he had taken a year earlier

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Clinical trials have demonstrated that tirzepatide produces substantial reductions in hemoglobin A1c levels (up to 2.5% in some studies) and significant weight loss (approximately 15-21% of body weight in obesity trials at the highest doses, with somewhat lower percentages in type 2 diabetes trials)