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This is in contrast to the situation in pigs (24) and in dogs (15), where total GLP-1 levels, estimated using a COOH-terminally directed RIA, are underestimated by 50% due to cleavage by NEP 24.11, as revealed in pigs using a NEP 24.11 inhibitor (24)

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Avoid use if you have active cancer or unexplained tumor growth, unless a specialist explicitly approves it, because GH/IGF-1 pathways can affect cell growth

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