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Can GLP-1s reduce cravings for alcohol or other substances

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These receptors mediate glucose uptake through a mechanism that involves phosphoinositide 3-kinase (PI3K) but is independent of protein kinase B (PKB)

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Muscle gain is a less common but possible explanation, particularly if you have significantly increased resistance training alongside treatment

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Nagashima M, Watanabe T, Terasaki M, Tomoyasu M, Nohtomi K, Kim-Kaneyama J, Miyazaki A, Hirano T: Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice

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