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The mechanism of action involves simultaneous activation of both GIP and GLP-1 receptors, which are naturally occurring incretin hormones

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This might happen if: Weight loss progress slows down Side effects are difficult to tolerate Blood sugar levels require better management Another medication may be better suited to the patients metabolism Instead of combining medications, providers typically transition patients carefully from one medication to another

Some providers specifically choose glycine-containing formulations for patients who report significant nausea with GLP-1 therapy

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