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2 Because this drug class lowers appetite, use has grown for the treatment of obesity

Juhyun Song, [email protected] This article was submitted to Neuropharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

No single canonical receptor binds the peptide with high affinity, and the systems-level pharmacology that defines the compound continues to be an active research question

Additionally, durability of effect requires ongoing treatment, with weight regain typically occurring upon medication discontinuation

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