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Eur Urol (2015) 68(4):67480

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"Furthermore, despite clomiphene citrate's association with significant increases in sperm concentration, it is not universally effective, with a meta-analysis indicating a significant increase in sperm concentration in approximately 60% of men." For men who have obesity and oligospermia but normal levels of testosterone and estradiol, "conventional pharmaceutical approaches like clomiphene may not be suitable," the authors wrote

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