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The LCIG treatment involves a continuous infusion of a carboxymethylcellulose aqueous gel directly into the proximal jejunum via a percutaneous gastrojejunostomy tube, with delivery by a portable infusion pump (Olanow et al., 2014)
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It is also noteworthy that nausea typically limits further dose escalation with subcutaneous GLP-1, but rarely occurs during intravenous GLP-1 infusion
Accordingly, several gut metabolic dysfunctions could contribute to long-term neuro-cognitive impairments in PASC, including: (i) perturbed gut-brain axis due to loss of SCFA producing intestinal flora, which may cause neuropsychiatric disorders 728
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