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GLP-1 RAs are increasingly used in the treatment of T2DM due to their multifaceted benefits, including improving glycemic control, reducing body weight, enhancing -cell function, and yielding favorable cardiovascular and renal outcomes [22]
The standard retatrutide dosage chart does not account for a 130-pound woman who has never used any GLP-1 compound
As a result, many patients find it easier to maintain a calorie deficit without the constant hunger associated with conventional dieting
Tirzepatide activates both GLP-1 and GIP pathways, while semaglutide primarily activates the GLP-1 pathway
In the ED: Fasting history is unreliable Treat as higher aspiration risk especially if symptomatic Anticipate vomiting and difficult visualization Practical considerations: Optimize positioning (ramped, head elevated, or slight reverse Trendelenburg) Use RSI when appropriate Minimize bag-mask ventilation Ensure suction is immediately available and functioning
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