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Caffeine affects blood glucose through at least three mechanisms: it antagonizes adenosine receptors (which normally improve insulin sensitivity), it stimulates catecholamine release (which promotes glycogenolysis), and it inhibits phosphodiesterase (raising cAMP and amplifying counterregulatory hormone signals)
Enhanced Nutrient Absorption: POTS can disrupt the digestive system, hindering nutrient intake
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Your body is getting used to the medication, and doses are usually lower in the beginning
LIMITATION The sample size in our study was small
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