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Diabetologia , 58(7), 1404-1412

GLP-1 medications blunt your brain's natural thirst signals along with your hunger signals, making it easy to forget to drink fluids

The Incretin Effect: Why Eating Is Better Than an IV Drip for Your Blood Sugar Here's a fascinating fact that researchers discovered decades ago: if you give someone glucose through a vein bypassing the gut entirely the insulin response is much weaker than if the same person swallows the same amount of glucose

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Hydration Supports Everything Adequate water intake supports metabolism, helps manage side effects (especially constipation), and prevents the fatigue that sometimes accompanies reduced food intake