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In this way, it is possible for the released insulin to act on A-cells , while glucagon usually does not have time to reach B-cells (half-life 1 - 3 minutes, in addition, most of the glucagon is usually taken up by the liver)
doi: 10.1097/MIB.0000000000001155 154 ZengWZhangQFengGLiuGWuFShenHet al
Induced ablation of ghrelin cells in adult mice does not decrease food intake, body weight, or response to high-fat diet