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While the exact experimental conditions (CCK concentration, incubation methods) differ in much of the literature, we directly tested conditions previously used to demonstrate that CCK peptide at 1 M enhanced GSIS in mouse islets and could not replicate those findings (Fig

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[11] In practice, the benefit of treating a true B deficiency in pregnancy, preventing anemia and neurological injury, is considered to far outweigh any theoretical risks, under the guidance of a healthcare professional