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Paik said

Compared to other weight loss drugs, using GLP-1 agonists increases the risk of pancreatitis (inflammation of the pancreas) by 9 times, bowel obstruction (blockage of the small or large intestines) by 4.5 times, and gastroparesis (a condition that slows or stops the movement of food from the stomach to the small intestine) by 3.6 times

Key Takeaways Diarrhea is a common gastrointestinal side effect of semaglutide, especially as the medication alters how quickly food moves through the digestive system

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(Epub 2016 Dec 5)