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However, the expression ofmiR-448 shows and opposite trend to that of NEAT1, and both competitively bind to ZEB1 to regulate tumor growth 154

During abiotic stresses, Ca 2+ signaling plays an important role by stimulation of Ca 2+ channels and causes an increase in cytoplasmic Ca 2+ levels for further downstream retaliations (McAinsh and Pittman, 2009

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