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While necessary for acute survival, this response generates an enormous quantity of reactive oxygen species (ROS) as collateral damage

B12 thins the blood and prevents blood stickiness

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Notably, mitochondrial autophagy downregulates mtROS levels by clearing damaged mitochondria, while deacetylases such as SIRT3 inhibit this pathway by enhancing antioxidant enzyme activity

Additionally, we observed that, in PTSD participants, GSH in the DLPFC (but not in the ACC) is elevated in cannabis users and in individuals with a history of mTBI (albeit a small n = 10 sample size)