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Microdosing GLP-1s: Reduce Inflammation, Support Cognitive Health The potential of microdosing GLP-1 for weight loss, inflammation, cognitive health, and more
By activating GLP-1 receptors in the hypothalamus and brainstem, these analogs promote satiety, leading to reduced food intake and weight loss ( Studies as Network Meta-analysis and clinical trials have shown that GLP1-RA can achieve a statistically significant decrease in HbA1C compared to placebo, as well as a weight reduction ranging between 1.3 and 8.65 kg ( With regard to cardioprotection, several mechanisms have been proposed
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Similarly, the STEP 4 trial found that patients who discontinued semaglutide and switched to a placebo for 48 weeks regained 6.9% of their body weight