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Although nausea was commonly classified as moderate due to its associated loss of appetite and significant weight loss, this was rather an expected effect than a true AE and also a reason why patients with IIH have been offered to be treated with GLP-1-RAs in the first place

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Pernicious Anemia Pernicious anemia, an autoimmune disease that destroys stomach cells, reduces the bodys ability to produce intrinsic factor

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Data show that there were 1,176 cases of acute and chronic pancreatitis following tirzepatide use reported between January 2023 and June 2026, 18 of which had a fatal outcome

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