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As a criterion for data inclusion, for a slope to be calculated for a peptide for an individual, at least three non-missing values were required for the peptide (out of four possible)

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For testosterone-adjacent compounds, the useful workflow is to identify the pathway first: HPG-axis signaling, GH-axis signaling, sexual-function signaling, tissue-repair signaling, or metabolic signaling

Reconstitution happens in a controlled environment