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Mun JG, Wang D, Doerflein Fulk DL, et al

5 4) Tendon & connective-tissue pathways (GHR up-regulation) In tendon fibroblasts, BPC-157 up-regulates the growth-hormone receptor (GHR) at mRNA and protein levels and augments downstream JAK2 signaling in response to GHmechanisms consistent with tendon repair biology (in-vitro)

By activating AMPK, MOTS-c forces the body to switch from storing fat to burning it for fuel, while simultaneously making cells more sensitive to insulin

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doi: 10.1016/S0140-6736(18)32279-7 274 SheaSLionisCKiteCAtkinsonLChaggarSSRandevaHSet al