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doi:10.17179/excli2020-3239 [54] Fusobacterium May Help Colorectal Cancer Grow and Spread
The peptide influences laminin-5 (LN-5) expression in a temporally sophisticated mannerinitially inhibiting LN-5 to promote cellular proliferation and differentiation, then upregulating LN-5 expression during middle and late healing stages to improve the matrix environment and promote epidermal cell migration
This pathway is particularly relevant for GLP-1 agonists because GLP-1 receptors in the brain play a crucial role in appetite suppression and metabolic regulation
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