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So I thought I'd just come on and explain a little bit more, not as advice, but just from my personal experience

World Health Organization World Health Organization (2003) GEMS/Food regional diets: regional per capita consumption of raw and semi-processed agricultural commodities/prepared by the Global Environment Monitoring System/Food Contamination Monitoring and Assessment Programme (GEMS/Food)

271,272,273,274 Additionally, uric acid regulates MAPK through phosphatase activity that inhibits the MAPK pathway

This is important to prevent waste product build-up and intracellular toxicity

Additionally, the interaction between NANOG, a gene associated with stem cells, and STAT3 increases MDR1 expression and the efflux of chemotherapeutic drugs, leading to chemoresistance development (70)