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Excessive FAs in the circulatory system promote insulin secretion from pancreatic beta cells, upregulate the expression of renal uric acid reabsorption proteins Glucose transporter type 9 (GLUT9) and urate transporter 1 (URAT1), and reduce the level of uric acid excretion protein ATP-binding cassette transporter G2 (ABCG2), resulting in elevated serum uric acid levels ( Figure 4 )
Its ability to increase energy expenditure has been known for over 60 years (125)
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When to Contact Your PlexusDx Provider Mild nausea, reduced appetite, and slight fatigue are expected and usually resolve within days
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