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The most common side effects are gastrointestinal symptoms including nausea, diarrhea, and abdominal cramping affecting 20-30% of patients

More patients receiving semaglutide discontinued treatment due to GI adverse reactions than patients receiving placebo during all clinical trials

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Real-world weight-loss effectiveness of glucagon-like peptide-1 agonists among patients with type 2 diabetes: A retrospective cohort study

This finding changed the medical consensus