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Additionally, anxiety can cause frequent night-time awakenings and early morning waking, reducing overall sleep duration and quality

The CSF-to-plasma ratio is approximately 0.4%, confirming that a small but definite amount of the drug penetrates the central nervous system (CNS) (Scheltens et al., 2026)

At 32 weeks, the semaglutide group showed significant increases in visuospatial, naming/language, and delayed recall scores compared to the placebo group ( P = .01, P = .05, and P = .04, respectively)

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The study cohort included more than 132,500 and 201,100 incident users of GLP-1s and sulfonylureas, respectively