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10.1016/j.bbi.2020.01.026 265

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The International Association for the Study of Pain defines it as pain resulting from a stimulus that does not normally provoke pain, and that definition matters because it distinguishes allodynia from hyperalgesia, where painful stimuli simply hurt more than expected

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So in theory, both support muscle growth and hypertrophy while shortening the time for muscle recovery following intense physical activity

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Assays, biomarkers, and phenotypic endpoints Biochemical and transcriptional readouts ERR target-gene panels spanning fatty-acid uptake/-oxidation (Cpt1b, Acadl/Acadm), OXPHOS (Ndufs, Uqcrc, Cox), TCA (Cs, Idh), and mitochondrial biogenesis (Ppargc1a, Tfam) provide proximal pharmacodynamic evidence of receptor engagement

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A., Modu, B., Calina, D., & Sharifi-Rad, J

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