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these agents should be used with caution in patients with existing cardiac conditions [15] [16] Bullous pemphigoid : A rare skin blistering condition has been reported with long-term use of some gliptins, as noted in MHRA safety communications
The ligand density observed in conformer 2 is sterically incompatible with the location of TM1 in conformer 1, which presumably explains why TM1 of conformer 2 is shifted away from the TMD core relative to TM1 in conformer 1 (Fig
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