The fat metabolism theory suggests GIPs effects on adipose tissue are crucial
Metabolic issues: Feeling constantly cold, chills, or a low body temperature (signs of metabolic acidosis) Severe gastrointestinal changes: Persistent diarrhea, vomiting, or a total loss of appetite Systemic changes: Unexplained tiredness, a fever or other signs of infection, unusual bleeding, bruising, or long-term concerns like osteoporosis In general, higher doses of topiramate are associated with an increased risk of adverse reactions
Those who cannot absorb B12 adequately from food require supplementation
It is not a drug, dietary supplement, food additive, cosmetic, or therapeutic agent, and must not be used in or on humans or animals
Verbeek, H