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Then, all animals were euthanized by bleeding after transection of the abdominal vena cava under anesthesia and the liver, heart, soleus muscle, gastrocnemius muscle, tibialis anterior muscle, extensor digitorum longus muscle, epididymal white adipose tissue, and brown adipose tissue were harvested and immersed in RNAlater solution (Qiagen, Venlo, Netherlands) for qPCR analysis
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Chronic activation of NF-B by oxidative stress can lead to sustained inflammation and the perpetuation of autoimmune responses [135]
In the unadjusted cause-specific-hazard regression model there was no difference in the risk of suicide or suicide attempts between patients treated with GLP-1 RAs compared with patients treated with SGLT-2 inhibitors or DPP-4 inhibitors, respectively, after 1 year and 3 years of follow-up, see Table 2