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Reconstitute away from direct light and use glass or high-grade polypropylene labware, avoiding prolonged contact with chelating or metallic surfaces that can strip Cu(II) from the tripeptide

IAPP toxicity activates HIF1/PFKFB3 signaling delaying -cell loss at the expense of -cell function

The solution is so concentrated that tiny measurement errors translate to massive dosing discrepancies

doi: 10.3389/fimmu.2021.799558 158 LambethJ

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