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A Phase 2 trial by Metabolic Pharmaceuticals found that while the compound was well-tolerated, it did not produce statistically significant weight loss versus placebo at the doses tested

Following reports of bacterial endotoxin in the pelvic cavity and menstrual blood 37 , and sub-clinical uterine infections found in patients with endometriosis 56 , Khan et al., 2017 proposed that microbes might activate inflammatory cascades by binding Toll-like receptors, and contribute to endometriotic lesion establishment, growth and progression

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