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For loose stools, hydration prevents the dehydration that diarrhea can cause
Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ
The initial muscle loss seen with GLP-1 RA treatment as well as the ongoing replacement of muscle with fat with treatment cycles involving treatment interruptions can result in unfavorable changes in body composition in patients with obesity that can have profoundly negative repercussions, and can exacerbate obesity-related metabolic and health concerns 14,15,16