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Lipid peroxidation has toxic effects on cancer cells by two mechanisms: one is further decomposition of peroxide phospholipids into active substances, depleting nucleic acid and protein and then leading to cell iron poisoning (Kagan et al., 2017)
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[1] Persistently high B12 levels warrant medical investigation, as they may signal liver disease, kidney dysfunction, or certain haematological disorders
In practice, activity pacing is guided by several key principles: (i) Understanding Energy Limits: Patients learn to recognize their personal energy thresholds, identify early signs of overexertion, and abstain from activities that exceed these limits [173]
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