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Participants were randomly assigned to receive weekly injections of retatrutide at doses of 1 mg, 4 mg, 8 mg or 12 mg, or a placebo for 48 weeks

However, alcohol can worsen gastrointestinal side effects common with this drug class and can affect blood sugar control, so once the medicine is licensed, patients should follow the prescribers specific guidance

Zepbound and Mounjaro contain the same active ingredient, tirzepatide

Weight Loss Benchmarks In SURMOUNT-1 (N=2,539, 72 weeks), tirzepatide 15 mg produced 22.5% mean body-weight reduction versus 2.4% for placebo [3]