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Pyroptosis can be categorized into four well-recognized signaling cascades, namely the classical, non-classical, caspase-3-dependent, and caspase-8-dependent pathways (159, 160)
To balance these trade-offs, hybrid strategies combining physical and chemical interactions have emerged as promising approaches
Animal studies show it accelerates healing of Achilles tendon injuries, medial collateral ligament tears, and other connective tissue damage
Tomlinson GE, et al
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