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This is denoted by the upper right quadrant of the eDISH plot
However, practical considerations matter
If these symptoms persist beyond the 16-week mark at the same intensity, it could indicate that the maintenance dose is too high
The key is keeping it consistently cold and dark
doi: 10.3389/fphar.2020.00886 Received 18 December 2019 Accepted 29 May 2020 Published 16 June 2020 Volume 11 - 2020 Edited by Bjorn Johansson, Karolinska Institutet (KI), Sweden Reviewed by Chieh-Hsin Lin, Kaohsiung Chang Gung Memorial Hospital, Taiwan
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