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Cardiovascular outcomes During accumulated follow-up time totaling approximately 39.0 person-years, three expanded MACE events were observed, yielding an incidence rate of 7.69 events per 100 person-years

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Additionally, Hallmark pathways such as IL2 STAT5 signaling and allograft rejection were upregulated, reflecting the heightened immune activation in tumors which could foster a hostile environment for tumor growth

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10.3177/jnsv.47.329 12 HiramatsuA.AikataH.UchikawaS.OhyaK.KodamaK.NishidaY.et al (2019)