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For example, DPP-4 cleaves BNP (132) into BNP (332), which is regularly detected in the plasma of patients with congestive HF [97]

Research indicates that genetic variation in GLP-1 receptor (GLP1R), glucose-dependent insulinotropic polypeptide receptor (GIPR), and metabolic genes like FTO and MC4R may influence individual response to GLP-1 agents, though clinical application is still evolving

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

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K., Chang, R