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A tricky thing with semaglutide is that GI symptoms (such as nausea, vomiting, and diarrhea) are the most common side effectsand each one can dehydrate you, indirectly contributing to fatigue

10.1016/j.jff.2023.105645 39 MatusheskiN.JefferyE

The FDA Category 2 Framework and the July 2026 PCAC Meeting In 2023, the FDA created a list of 19 peptides classified as Category 2: substances that do not currently fit the five legal compounding categories but have enough clinical interest and accumulated safety data to warrant regulatory review