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4 and 5, Extended Data Fig

Golberg, N

Loss of CNS GIPR augments weight loss with GLP-1R agonism To examine whether CNS GIPR is required for the additive weight loss effect of combination treatment with mGIPR-Ab and clinically approved GLP-1R agonists, HFD-fed Gipr fl/fl control mice and Gipr Syn/ mice received IP dosing of either vehiclevehicle, dulaglutidevehicle or dulaglutidemGIPR-Ab combination treatments

As a result, it has become a cornerstone in the treatment of diabetes and is now at the center of the conversation about weight loss drugs and their potential risks

Kurbasic M, Garcia AM, Viada S, Marchesan S