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BPC-157 also modulates the nitric oxide (NO) pathway, which plays a crucial role in vascular function and tissue protection

These side effects may be more common after initiation and during dose escalation

FIGURE 5 FIGURE 6 It is known that APN is produced mainly by adipose tissue, and we therefore investigated the mRNA expression in the subcutaneous fat of the three groups of mice

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It is also possible that there was more protein aggregation at pH 7 than pH 5 as previous research has shown that protein aggregates can form at neutral pH due to hydrophobic interactions, even if the isoelectric point is at a different pH (Vetri et al., 2007)