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Moreover, GLP-1RA reduced the risk of MACE by 14% in the overall diabetic population, with an apparent greater effect in patients with established CV disease (16% vs 6% reduction, respectively), although the lack of significant interaction between subgroups does not allow to separate them [12]
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P-gp contributes to limit the entry of toxins into the CNS from the bloodstream as well as to the brain-to-blood clearance of beta-amyloid
This review synthesizes current research on ferroptosis mechanisms in CHD and emerging clinical intervention strategies
