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The peptide downregulates TNF- (6.2-fold reduction) and IL-6 (4.1-fold reduction) while upregulating anti-inflammatory IL-10 (8.1-fold increase)[12]
This is psychologically challenging
BPC-157 delivers the localized signal
The NHS notes that taking up to 2,000 micrograms daily is unlikely to cause harm in most people, though there is generally no benefit to such excessive amounts without confirmed deficiency
A 2009 study looking at dosing rats with oral BPC-157 found that the effectiveness of the peptide therapy was certainly present and that positive effectiveness was present
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