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In terms of geography, the North America region dominated the total market for GLP-1 receptor agonists, owing increasing prevalence of diabetes and obesity, premium-priced GLP-1 drugs, and strong pipeline of potential candidates in the developed countries
Stupnisek et al., 2015
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Lifestyle interventions (including diet, exercise and behavioural changes) are the cornerstone of obesity management with diverse benefits, but even the most intensive lifestyle interventions result in up to 10% mean weight loss (WL) and weight maintenance remains a challenge, as 80% of WL is expected to be regained over the next 5 years [4, 5]
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