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Shake things up by trying new exercises, increasing intensity, or tweaking the duration to give your metabolism a fresh challenge

These drugs modulate dopaminergic signaling in the mesolimbic system, the brains reward circuit, which is also implicated in addiction

Neither medication manages blood sugar or weight to the same degree as newer versions, but these older drugs are still good options for people with mild diabetes who are not overweight, says Sue Pedersen, an endocrinologist and obesity medicine specialist at the C-endo diabetes and endocrinology clinic in Alberta