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Relevant drugs were then screened in the natural product database using a model of the GPX4 protein binding (Fig

Even strong oxidative stress does not produce appreciable amounts of oxidized e-GST

Induction of SLC25A39 protein levels was generalizable as two additional cell lines from distinct tissue origins (K562 and HEK-293T) displayed similar responses to BSO (Fig

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A randomized controlled trial on the effect of metformin in CHD patients without diabetes showed that it (2000 mg/day, P.O for 12 months) not only decreased oxidative stress but also lowered left ventricular mass (LVM) and improved blood pressure [227]