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As a selective melanocortin 1 receptor (MC1R) agonist, afamelanotide is applied in experimental settings to probe the cAMP-mediated melanogenesis cascade the intracellular signaling pathway through which MC1R governs pigmentation biology in melanocyte cell models

doi: 10.1016/j.jsbmb.2014.01.009

At a constant concentration of GSH with varying concentrations of MBB, the apparent K m , Vm and specific activity were respectively determined to be (8 to 9) molar

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