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Accordingly, culturing human islets in the presence of a DPP-4 inhibitor resulted in increased levels of intact GLP-1 (98, 101, 104), increased insulin secretion (98, 99, 101, 104), and improved -cell survival (99, 101)
Porter, Carnitine Metabolism and Human Nutrition, CRC Press, Avr
doi: 10.1136/ebmental-2021-300291 9 KleinCCTopalianAGStarrBWelgeJBlomTStarrCet al
Thats why the FDAs own technical staff has recommended against expanded access, and the public health group Partnership for Safe Medicines calls them "popular, unproven, dangerous. As Peter Kolchinsky, managing partner of biotech investor RA Capital Management, puts it: Is the FDA going to stand on science or is it going to permit all kinds of snake oil to be readily available? The FDA meeting will last two days
The other thing is that theres a big difference between a person being depressed [versus the GLP-1 side effects], which they have started looking into
